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Pepperoni Pizza. Nutrition Facts. Pepperoni Pizza. Serving Size: slice (111 g grams) Amount Per Serving. Calories from Fat 119. Calories 313 % Daily Value * 20% Total Fat 13 g grams. 29% Saturated Fat 5.7 g grams. Trans Fat 0.3 g grams. Polyunsaturated Fat 2.3 g grams.
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Jan 01, 2020 · According to the U.S. National Library of Medicine, a medium-sized slice of Papa John's Pepperoni Original Crust Pizza has 230 calories, whereas a slice of Little Caesars' 14-inch Pepperoni Pizza has 280 calories. Per the NHLBI, as portion sizes get larger, a single slice of pepperoni pizza can have 450 calories.